San Mateo County, California
South San Francisco Real Estate and Local Guide
A diverse working and biotech city on San Francisco Bay, blending long-standing industrial roots with a large life-sciences employment base. Ranked Realty pairs verified local data with the agents who know South San Francisco best.
About the area
Living in South San Francisco, CA
Called "The Birthplace of Biotechnology" after Genentech opened there in 1976.
The housing market
Homes in South San Francisco
- About 61% of housing units are owner-occupied.
- About 59% of homes are single-family structures.
- The median home value is about $1.16 million.
Landmarks and lifestyle
What makes South San Francisco home
Sign Hill
Hillside bearing the concrete "South San Francisco The Industrial City" letters
Oyster Point Marina/Park
Bayfront marina and park at Oyster Point
South San Francisco City Hall
Historic building modeled after Philadelphia's Independence Hall
Orange Memorial Park
Large park with ball fields, pool, and sculpture garden
Sign Hill Park
About 30 acres of open space with hiking trails
Neighborhoods
South San Francisco areas to know
Westborough
Hillside residential neighborhood on the west side
Buri Buri
Established residential neighborhood
Sunshine Gardens
Residential neighborhood
Winston Manor
Residential neighborhood
For agents
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Local facts on this page are verified against public sources as part of the AppWT local-data project. Data reflects the most recent available figures.